Murray, who suffered an elbow injury in March and made his return from a five-week layoff on Wednesday after a first-round bye, won the opening set in 48 minutes before losing concentration.
In fact, barring 2014 when Stan Wawrinka won the title, no player apart from the quartet has even been involved in the men's final at Melbourne Park since 2008.
Nick Kyrgios's Australian Open ended with a gallant fourth round defeat by an inspired Grigor Dimitrov on Sunday but the maverick talent leaves Melbourne Park after winning over a nation.
With colours resembling famous candies and lolly brands, Nike splashed bright hues to drive sales to younger fans
Britain will attempt to win the Davis Cup for the first time in 79 years this weekend when they take on Belgium in Ghent, although if they do succeed the Scottish town of Dunblane could argue its name should be enscribed on the trophy.
Images from Day 3 of the 2020 US Open in New York, on Wednesday.
Juan Martin del Potro delivered a huge blow to Britain's hopes of retaining the Davis Cup when he beat Andy Murray 6-4, 5-7, 6-7(5), 6-3, 6-4 in a five-hour thriller as Argentina grabbed a 2-0 lead in their world group semi-final on Friday.
But for the 23-year-old Bouchard, a former world number five who has slumped to 56th in the rankings, it was another blow after her first-round exit in Indian Wells.
Rediff.com presents the early surprises at the year's final Grand Slam
Defending champion Sloane Stephens was sent packing from the Miami Open on Sunday after a 6-3, 6-2 loss to Germany's Tatjana Maria in the third round.
Top seed Serena Williams dropped the second set before bouncing back to beat compatriot Christina Mchale 6-3, 5-7, 6-2 in second-round action at the Miami Open in Florida on Thursday.
Top seed and defending champion Roger Federer returned to form to beat Japan's Kei Nishikori 6-4, 7-6(4) and reach the Shanghai Masters semi-finals on Friday.
Twice Shanghai Masters champion Roger Federer was far from his best against Spain's Roberto Bautista Agut but did enough to reach the quarter-finals with a 6-3, 2-6, 6-4 win on Thursday.
Both won in style on Sunday, with Spanish fifth seed Nadal pouncing on Guido Pella's serve to break the Argentine five times en route to a 6-3, 6-2 victory in sizzling afternoon heat on the stadium hard court.
The 23-year-old Australian, who will be seeded 15th at Wimbledon, says he is in his best shape ever, and he is being talked about as serious challenger for this year's title.
Australian maverick Nick Kyrgios blazed past Feliciano Lopez with a barrage of aces to reach the semi-finals of the ATP 500 Fever-Tree championships at Queen's Club on Friday. The 23-year-old was in dazzling form as he claimed a 7-6(5), 7-6(3) victory over the defending champion to set up a clash with top seed Marin Cilic, who breezed past Sam Querrey.
The 36-year-old was all over the world number 58 throughout a one-sided contest under the Rod Laver Arena roof, breaking three times to win the opening set in 33 minutes.
Rafael Nadal's Australian Open quarter-final curse struck again on Tuesday, an injury forcing the top seed to retire in the fifth set against Croatia's Marin Cilic.
Rafael Nadal put in some late-night overtime to drag hosts Spain into the Davis Cup semi-finals but Novak Djokovic's hopes were dashed in excruciating fashion as Serbia bowed out on Friday.
The draw for the first Grand Slam of the season was made on Thursday and the top seeds could face some early tests of their credentials when play gets underway in Melbourne on Monday.
A summary of sports events and sports persons, who made news on Monday
Home favourite Kei Nishikori defeated Frenchman Richard Gasquet 7-6(2), 6-1 in the semi-finals of the Japan Open on Saturday, setting up a final against Russian qualifier Daniil Medvedev.
Photos from the Wimbledon matches on Day 1
Osaka survives test to reach last 16
Britain's Andy Murray enjoyed a routine win over Argentina's Juan Monaco to ease into the third round of the tennis tournament at the Rio Games on Tuesday, while Spain's world number nine David Ferrer was knocked out.
Rafael Nadal fired hosts Spain into the Davis Cup final as he joined Feliciano Lopez to win a thrilling late-night doubles and seal a nail-biting 2-1 victory over Britain on Saturday.
Bulgarian Grigor Dimitrov kept cool in the Rod Laver Arena maelstrom to knock home favourite Nick Kyrgios out of the Australian Open in a fourth-round thriller on Sunday.
Relief was at hand, however, with a cool change blowing over the city and the temperature expected to fall back below 30 by the evening.
Williams, a record 23-times Grand Slam champion, will be returning to the All England Club for the first time since giving birth to her daughter last September.
World number one Rafael Nadal set a new record of winning 50 consecutive sets on a single surface by beating Argentine Diego Schwartzman 6-3, 6-4 on Thursday to reach the Madrid Open quarter-finals.
Raucous home support for holders Argentina did not make up for the absence of Juan Martin del Potro and Federico Delbonis on Friday as they fell 2-0 behind to Italy in the first round of the Davis Cup.
Lucas Pouille crowned a glorious French charge at the U.S. Open on Sunday by ousting 14-times grand slam singles winner Rafa Nadal in a five-set thriller. The 22-year-old Pouille, seeded 24th, won a deciding tiebreak 8-6 to complete a 6-1 2-6 6-4 3-6 7-6(6) marathon victory and join compatriots Jo-Wilfried Tsonga and Gael Monfils into the last eight at Flushing Meadows.
Check out some of the up-and-comers who could cause an upset at Wimbledon this year.
A summary of sports events and sports persons, who made news on Sunday
A tenacious Roberto Bautista Agut battled back to beat world number one Novak Djokovic 1-6, 7-5, 6-3 and advance to the quarter-finals of the Miami Open on Tuesday as the Spaniard claimed his second win over the Serb this year.
Former world number one Serena Williams looked sharp in her return to the hardcourts after a week-long break, soundly defeating Daria Gavrilova 6-1, 6-2 on Monday to advance to the second round of the Cincinnati Masters.
Czech defending champion Katerina Siniakova fended off Maria Sharapova in a fiercely contested match at the Shenzhen Open on Friday to set up a final with world number one Simona Halep.
The Frenchman, seeded five, had no answer to left-hander Muller's swinging serve as he bowed out 6-4, 6-4.
Rafael Nadal swept into the quarter-finals of the Italian Open on Thursday with a ruthless 6-4, 6-1 victory over Canadian teenager Denis Shapovalov. The top seed, who will reclaim the world number one ranking from Roger Federer if he wins his eighth title in Rome, turned in a near-flawless performance, losing only five service points as he honed in on victory in an hour and 22 minutes.
Naomi Osaka eased into the second round of the Italian Open on Monday with a 6-0, 6-3 victory over former world number one Victoria Azarenka, on a day in which local favourite Roberta Vinci called time on her career.